![]() ![]() Thus, up to 240 protons per glucose are translocated across the membrane. This involves vectorial translocation of up to 120 protons by the respiratory chain, which will be taken up again by the ATPase. For example, a bacterium respiring a single molecule of glucose with oxygen gains about 30 ATP ( Rich, 2003). As the ATPase takes up 3–4 H + per ATP ( Cross and Müller, 2004 Steigmüller et al., 2008 Petersen et al., 2012), which before have been pumped out driven by respiratory or photosynthetic electron transport, proton translocation across a membrane is the most common process in living cells. ![]() The pmf is then used to drive ATP conservation by the membrane-bound ATP synthase (or simply ATPase), which is also an electrogenic proton transport system. The most important electrogenic vectorial processes are proton translocation during respiration and photosynthesis, which build up the proton-motive force (pmf, composed of the trans-membrane proton gradient, and membrane potential). By contrast, electrogenic transport (e.g., symport of 2 H + per anion A –) affects the electrical potential across the membrane. Some vectorial processes – named electroneutral – are not going along with a net charge transfer (e.g., transport of an anion A – in symport with a single proton H +). The resulting pH effects are transient and compensated by counteracting cyclic transport processes. By far more common are vectorial processes which translocate protons or metabolites across a membrane without changing their overall amount. As such reactions change the amount of protons in the system they are named scalar. First, production or consumption of acidic or basic metabolites results in permanent pH effects. Our approach allows for studying a broad variety of proton-related metabolic activities at micromolar concentrations and time scales of seconds to minutes.Īll living cells, mitochondria, chloroplasts or bacteria cause various types of pH changes. We could verify the kinetic simulation parameters found with proton.exe using series of increasing additions of the reactants. This method gave lower but more realistic values than logarithmic extrapolation. H +/e – ratios of electron-transport driven proton translocation were calculated by simulation with proton.exe. To study electron-transport driven proton translocation, the membrane potential was neutralized by addition of KSCN (100 mM). For reductant pulse experiments, small amounts of H 2-saturated KCl were added to cells incubated under N 2 with an excess of one of the above-mentioned electron acceptors. Two types of experiments were performed: In oxidant pulse experiments, cells were kept under H 2, and micromolar amounts of sulfate, nitrate or nitrite were added. We analysed sulfate uptake by proton-sulfate symport, scalar alkalinization by sulfate reduction to sulfide, as well as nitrate and nitrite reduction to ammonia, and electron transport-coupled proton translocation. In our experiments, the versatile sulfate-reducing bacterium Desulfovibrio desulfuricans CSN (DSM 9104) was used as model organism. The simulation includes changes of the transmembrane ΔpH, membrane potential and ATP gains, and demonstrates the principles of chemiosmotic energy conservation. The program applies Michaelis-Menten or first-order kinetics to the metabolic processes and allows for parametrization of simultaneously ongoing processes. ![]() Recorded data were used for simulating substrate turnover rates by means of a new freeware app ( proton.exe). ![]() Proton release and uptake induced by metabolic activities were measured in non-buffered cell suspensions by means of a pH electrode. Institute for Chemistry and Biology of the Marine Environment, Carl-von-Ossietzky University of Oldenburg, Oldenburg, Germany. ![]()
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![]() ![]() He is also a technical writer and works as a Node.js consultant, helping clients build and maintain their Node.js applications. If you're interested, feel free to follow along.Kelvin Omereshone Follow Kelvin is an independent software maker currently building Sailscasts, a platform to learn server-side JavaScript. In the next article, we will discuss how to split an application into multiple containers and have them work together to compose your application. Volumes will become a common practice in the upcoming chapters as we focus on data persistence. ![]() If you want to explore further, you can refer to the official documentation. I hope you have gained a good understanding. This article covered two types of volumes. With just Docker installed, the possibilities are endless! □□ Conclusion Similarly, you can compile C++ source code without installing g++, develop Java programs without installing JDK, and even use MongoDB without installing it directly on your machine. With volumes, you can avoid installing npm but still run npm init. In the above example, package.json is actually generated inside the container. Then, run npm init inside the container.Īfterward, check if package.json has been created on your machine.ĭocker run -v ~/app:/app -workdir /app node:slim npm init -y ![]() Let's see a demo:Ĭheck that there is no package.json inside ~/app on local machine.Ĭonnect the ~/app folder on your machine with the /app folder inside the container. Now, let's introduce another approach called Host Volume, which directly connects a specific folder on your machine with a folder inside the container. The previous approach, where you create a volume before using it, is called a Named Volume. This proves that even when a container is stopped, the data is still preserved in the volume, and the next container can successfully access the data left by the previous container. It's worth noting that these three commands are executed in different containers. Then, create a file named "file" inside the container.ĭocker run -v db-data:/db/data -it ubuntu ls -la /db/dataĭocker run -v db-data:/db/data -it ubuntu touch /db/data/file Initially, confirm that there are no files in /db/data. Alternatively, you can substitute it with the path where your database stores data. In this example, we are assigning the db-data volume to the /db/data location within the container. Docker has now added a folder on your machine for the volume. After completion, you will see an additional volume. We first create a volume called "db-data". How to use named volumn Step 1 - Creating a named volume This allows us to preserve the container's data. Importantly, even if the container is deleted, the data remains intact in the volume. As they are connected, any changes made to the folder within the container will reflect in the local folder. When you use a volume, Docker creates a local storage area on your machine, usually under /var, and establishes a connection between this folder and a specific folder inside the container. Let's take a look at the following diagram provided. To address this issue, we can utilize volumes to ensure data persistence.īasically, Volume is utilized to store data within containers. This means that if we need to upgrade the version of MySQL and decide to shut down the running mysql:5.5 container to start a new mysql:5.7 container, the data stored in the database would be lost. If you haven't read the previous article, " Pushing Your Docker Images to Docker Hub: A Step-by-Step Guide", I recommend taking a look at it first.Īs I mentioned before, each container operates in isolation. This is the third article in the Docker Series. You can find the Chinese version at Docker 實戰:使用 Volume 保存容器內的數據. ![]() ![]() O&O ShutUp10 is just one tweaker, but one that is updated regularly to address issues that arise from new Windows 10 releases and to add options to disable new features in the new versions of the operating system. If you noticed start up issues, this one may fix them for you or speed things up at the very least. The program started quickly in previous versions, at least on the systems that I tried it on. The release notes suggest that the startup of the application has been optimized in the new release. You can check out our guides on disabling Meet Now and disabling News and Interests, if you prefer to disable these features manually. The option to disable the News and Interests widget was not listed on a test system, but the feature was not available on the device yet. The options are displayed in the Miscellaneous group in the program. NEW: Disable news and interests in the task bar for current user NEW: Disable news and interests in the task bar on this device The computer will, however, remain in the your O&O. NEW: Disable “Meet now” in the task bar for current user O&O Syspectr can be uninstalled via the Windows Control Panel just like any other Windows program. ![]() NEW: Disable “Meet now” in the task bar on this device The new version of O&O ShutUp10 supports disabling both features for the current user or on the entire device. The new version of Windows 10 introduces new features, including the News and Interests widget on the taskbar and Meet Now, also in the taskbar. Support for Windows 10 version 21H1 is not the only new feature of the application. Other versions of Windows can be upgraded using installation media or other means. Currently, only select devices, running Windows 10 version 2004 or 20H2, receive the update offer via Windows Updates. ![]() The program provides tips and information so it is clear which functions can be safely deactivated and which not. The update is rolled out gradually to the entire Windows device population. The solution The new freeware O&O ShutUp10++ enables users to see all Windows 10 and 11 security settings on one simple page and to deactivate those that share sensitive data which they are not comfortable with. Microsoft released Windows 10 version 21H1 last month. You can check the installed version of the program by selecting Help > About. ![]() ![]() The new version installs without issues over existing installations of the program configured tweaks should remain as they are, provided that the tweaks are still supported by the new version of the Windows operating system. O&O ShutUp10 presents you with all essential settings to help achieve this in one location – you need no previous IT knowledge, and there is no need to change the Windows 10 system settings manually.O&O ShutUp10 version was released on June 2, 2021. Your privacy should be up to you and not anyone else.
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Adjust the format and share with your friends on social media platforms.ĬapCut is a free all-in-one video editor and video maker application with everything you need to create stunning, high-quality videos.Custom video export resolution, HD video editor supports 4K 60fps exports and.Extract audio, clips, and recordings from videos.Add millions of music clips and sound effects to videos.Add movie-style video filters or freely adjust video brightness, contrast, etc.Edit videos with hundreds of trending effects, including Glitch, Blur, 3D, etc.Match video content with diverse filters that are updated weekly with the latest trends.Subtitles can be added to the timeline of video tracks and can be moved and adjusted in one step.Add text to videos with different fonts and styles, choose unique text templates.It offers powerful tools to help users create engaging videos with music and text overlays, transitions, filters, stickers and more in an easy-to-use interface. 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CapCut is a free mobile video editing app created by Bytedance Pte.Text-to-speech: apply text-to-speech in multiple languages and voices.Auto captions: automate speech recognition and subtitles in videos.The stabilizing feature keeps video footage steady.Easy to arrange and preview clips on multi-track timeline.Use the chroma key to remove specific colors from videos. ![]() Edit videos to create smooth slow-motion with the optical flow feature and speed curve tool.Keyframe video animation is available for all settings.Explore transition options with awesome effects on and between clips.Highlight the best moments with the freeze feature.Animate video clips with incredible zoom in/out effects.If you create content on TikTok regularly and want a feature-packed video editor for editing videos on Android or iPhone, you’ll love CapCut developed by the makers of TikTok. Isn’t a good fit for editing longer videos, like for YouTube or vlogs. Adjust video speed from 0.1x to 100x, and apply speed curves to clips. 1) CapCut The feature-rich mobile video editing app.Trim and shorten clips and split or merge videos.Show your personality and go viral on TikTok, YouTube, Instagram, WhatsApp, and Facebook! CapCut offers easy-to-use video editing functions, free in-APP fonts and effects, free advanced features such as keyframe animation, smooth slow-motion, chroma key, and stabilization, to help you capture and snip moments.Ĭreate fancy videos with other unique features: auto captions, text-to-speech, motion tracking, and background removal. ![]() ![]() Monitor all backup tasks in one fell swoop: Stop receiving hundreds of emails to check the backups of your clients Edit and configure backup schedulings remotelyĩ. Detailed information on the monitored computersħ. ![]() Management of workgroups, computers and jobsĥ. Comprehensive reports and error detailsĤ. Monitor all your backups from a single web panelģ. Monitor all the backups remotely in a centralized way:Ģ. Iperius Console is accessible by a common browser, a dedicated Windows/MAC application, or through mobile apps You can configure custom groups, accounts and related permissions. You can use it to update Iperius Backup, change job schedulings and run backup jobs remotely. It easily allows to view backup results, error details, and the health status of PCs, Servers and Virtual Machines. With a single license you can back up and unlimited number of databases without any restriction.Ĭlick here to buy Iperius Backup Advanced DB.Iperius Console is a powerful monitoring tool and centralized dashboard for Iperius Backup. MySQL and MariaDB backup is available starting from the Advanced DB edition, that also allows to all other major DBMS: SQL Server, Oracle, PostgreSQL. In the final panel, choose a name for the backup job and save it clicking OK.Īfter you saved the backup job, you can immediately run it by right click. The destination list can be left empty, while in the next panels you can configure a detailed scheduling, to perform automatic backups at specific days and times, and the e-mail notifications, to be always informed about the backup results and possible errors. Once all the necessary settings have been configured, save the MySQL backup item clicking the button OK, and proceed with backup job configuration. The additional copy can be made to all the destinations allowed by Iperius, therefore NAS devices, FTP or SFTP servers, RDX drives, LTO tape drives, cloud spaces such as Google Drive, Dropbox or Amazon S3, computers in the network, external USB drives, etc.Īs already said, these additional destinations can be specified in the panel “Destinations”, as you can see in the picture below:Ĭoming back to the MySQL backup configuration, there are some other settings to be explained: you can set the advanced backup verification, add an extension or a custom text (also using special variables) to the backup file name, choose file encoding if UTF8 or Unicode, enable zip compression and the AES 256 bit encryption. In this case, you can add an FTP destination in the “Destinations” panel. In fact, this special item wouldn’t need additional destinations (it already includes one), but, for example, you might want to transfer backup files to an FTP server. The option “ Copy backup files in the job destinations” allows you to automatically make a further copy of the database backup files in the job destinations. Using the option “ Include in the backup the following objects” you can select the database objects you want to include in the backup (by default Iperius includes the table structures and data, but you can also include users, stored procedures, triggers, etc.). You can also use some special variables to customize the folder name with the computer name, the week day name, etc. The next option is the destination folder, so the folder where to save the database backup files. As shown in the picture below, you can automatically back up all the databases on the server, select a single database (you can create in the same backup job an individual item for every database or server, each one with its specific options), or type several database names separating them with commas. Once you’ve specified these data, you can immediately test the connection using the specific button.Īfter the account has been created, you can select it in the item configuration window, and move on to configure the next options. You need the server IP address or name, the username and assword. The first step consists in creating and selecting an account to connect to the database server. With a single license you can run the automatic backup of unlimited servers and unlimited databases (even website databases if your ISP allows external access to them).įrom the main window of Iperius, first create a backup job using the appropriate button:Ĭlick on the button that allows to add a MySQL/MariaDB database backup: Backup files can be automatically transferred by FTP, FTPS and SFTP or to Cloud services such as Google Drive, Dropbox or Amazon S3. It can back up local or remote databases without any service interruption ( hot backup). 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I found mp3s, wav,flac, and wma and the one special wav file of a very very very young Joan Baez/Imagine-a song that is very special to me. Not sure what I had retrieved, I just put it aside until now. I had had a thunderous "blue screen of death" about a year ago and tried a recovery as many of my files that I could. Did a retake and found 3745 files mp3 only. I found on one drive alone 3.86GB of mp3 only. Ohhhh! my!!!! I don't know if this is alot but to me it is. So, before I downloaded, I ran a search of all 4 drives. I wonder just what do I have in the way of music on my computer since I use the likes of Kevin MacLeod in some of my works. I decided to try this program after reading all the input. So, with that, I know nothing about tagging etc, and not very familiar with what's out there - proprietary, freeware, shareware, GNU etc. I am now an artist and strictly an end user. My tech experience was way way before Bill Gates/Microsoft. OMG!! First, I will not even get into the tech arena here. Furthermore, I need something that can focus on IDv3.2 such as Ex Falso to get my Japanese music's tags to display correctly. It takes a lot of work to tag in MP3 Tag Express unlike other stuff I'm used to. ![]() This program was close to replacing Mp3tag for me, but it is Mp3tag that will stay. As a personal requirement, I want this ease of access because I get a lot of music from Nicosound (rips MP3s from Nico Nico Douga videos). ![]() * Multi-Edit does not let you change the title of the song. Even Mp3tag lets you double click on distinct fields in the file list and edit them on the spot. I would expect double clicking to open Multi-Edit at the very least. ![]() MP3 Tag Express needs you to click on a file, click on Edit Tags to access a dropdown menu, then choose something to edit. Most taggers need you to click on a file, then a field to edit. A tagger should focus on tagging files, so why is tag editing harder to access than playing files? I'd expect that from a music player like foobar2000 or Winamp - not a tagger! Web devs know to rate the staying time of viewers by the number of mouse clicks they must make before they reach their destination. * Double-clicking plays a file instead of lets you change tags. I hate seeing titles like ?, so I delete IDv3.1 tags through Mp3tag (Windows) or EasyTAG (Cross-platform). The problem is that I've never seen IDv3.1 tags work with Japanese. This is a killer for me because a ton of Linux music players read IDv3.1 tags first. * The program automatically tags both IDv3.1 and IDv3.2 on files. * As a personal requirement, I am glad to see Grouping is shown and editable by default. * There is convenient functionality for using the clipboard to move tags around fields. * I tried to tag a song with Japanese and was successful. * All options are easily seen and accessed. It's better than applying tags and having things auto-save. But unfortunately I don't think I will continue using this product. I'm glad the developer is watching these comments. ![]() ![]() Nintendo Switch users are the one that’ll have to wait for much longer, since the studio announced that it won’t be ready until July 25 of 2023. On PS4 and Xbox One, it won’t be out until April 4. The newest generation versions (Xbox Series X|S, PlayStation 5, and PC) will launch this coming February 10. Hogwarts Legacy will have a phased launch over every available platform there is right now. The pre-order numbers have been enough so far to earn it the fourth place of the list: Avalanche game is already one of the most sold titles on the platform at this time. In fact, according to data gathered by SteamDB, the Warner Bros. Hogwarts Legacy will go on sale this coming month, but everything seems to indicate that it’s already soaring on the sales lists. If quality is good gargantuan launch incoming, easily one of the biggest of 2023 /TNM93kPT3Z- Benji-Sales JanuHogwarts Legacy, in the Top 4 selling games on Steam What exact setting caused that? I been having vram running out on my 6800xt 16gb vram.Hogwarts Legacy is the #1 Most Wishlisted game on Steam, preorders are ranking in the Top 4 Selling games on Steam 5 weeks before launch, and I'm hearing VERY strong things about console preorders When I first started it wouldn’t even launch. I woke up this morning and tried to launch the game. I have put about 50 hours into the game, and I was playing last night just fine. Capped it to 30 and it is really smooth except some stutters due to low combined RAM available for the game on the Deck. So this is an issue that just started for me and I cannot figure this out. I am running FSR2 Quality with Medium settings except View Distance, Sky Quality, Fog Quality which are low. Originally posted by MindBlank:I have around 25 hours played on the Deck. ini is perfect until you get the broom, then unusable, at least on my system. ini where it nicely empties the framebuffer once VRAM usage hits 6GB. So I disabled this and I'm running stock. This usually happens when you are using the broom and it needs to load a lot of stuff quickly. ini mods and while there is 0 stutter, these settings do mess with emptying the framebuffer for the GPU and quickly exceeds the 16GB's available, making it unplayable. Hogwarts Legacy - Hogwarts Legacy: Digital Deluxe EditionThe Hogwarts Legacy Digital Deluxe Edition Includes:-Thestral Mount-Dark Arts Battle Arena-Dark Arts Cosmetic Set-Dark Arts Garrison HatAbout the GameHogwarts Legacy is an open-world action RPG set in the world first introduced in the Harry Potter books. Or maybe it is Steam Deck's 30fps cap in the settings, I don't know.Īnyway, looks better than low, plays well. However, outside of some castles, mainly smooth evenly paced locked 30 fps.Ĭompared to locked to 4k at 30fps on my PC, it is much smoother feeling on the Deck, even though no stutter drops on the PC. There is plenty of space/storage on this computer and no virus protectors. My computer shows the directX is fully updated on a 64-bit operating system (ARM-based processor). Baldur’s Gate 3 trhá na Steamu rekordy, lape na paty Hogwarts Legacy. Capped it to 30 and it is really smooth except some stutters due to low combined RAM available for the game on the Deck. I have the game downloaded and installed, ready to launch on an activated Windows 11 Pro - fully up to date. I have around 25 hours played on the Deck. ![]() |
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